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effects_of_miscarriage_on_breast_cancer_risks [2015/09/10 13:34]
marri2 [Effects of Miscarriage on Breast Cancer Risks]
effects_of_miscarriage_on_breast_cancer_risks [2017/05/26 08:00] (current)
marri
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 ==========Effects of Miscarriage on Breast Cancer Risks========== ==========Effects of Miscarriage on Breast Cancer Risks==========
  
-//Research Synthesis Paper//: ​[[http://​marri.us/​abortion-breast-cancer|Induced ​Abortion ​and Breast Cancer]]+//(See [[biology_of_the_abortion-breast_cancer_link|Biology of the Abortion-Breast Cancer ​Link]])//
  
 =====1. First-Trimester Miscarriage===== =====1. First-Trimester Miscarriage=====
  
-In her first trimester, the mother’s ovarian production of estrogen and progesterone (in response to fetal hCG((The embryo’s production of hCG (human chorionic gonadotropin) acts as a chemical signal and causes the mother’s ovaries to increase her production of estrogen and progesterone before the embryo is implanted in the mother’s womb. These hormones sustain the pregnancy. ))) maintains the pregnancy. Early miscarriage is often a response to hormone levels insufficient to maintain the pregnancy, due to an abnormality that inhibits the embryo from producing sufficient hCG or to the mother’s ovaries’ failure to respond to the hCG. The levels of estrogen and progesterone during an abnormal pregnancy that result in a first-trimester miscarriage are insufficient to stimulate breast development. As the breasts were never stimulated to grow, the mother normally has no change in breast cancer risk.((Janet R. Daling, Kathleen E. Malone, Lynda F. Voigt, Emily White, and Noel S. Weiss, “Risk of Breast Cancer among Young Women: Relationship to Induced Abortions,​” //Journal of the National Cancer Institute// 86 (1994): 1584-1592.))+In her first trimester, the mother’s ovarian production of estrogen and progesterone (in response to fetal hCG ((The embryo’s production of hCG (human chorionic gonadotropin) acts as a chemical signal and causes the mother’s ovaries to increase her production of estrogen and progesterone before the embryo is implanted in the mother’s womb. These hormones sustain the pregnancy.))) maintains the pregnancy. Early miscarriage is often a response to hormone levels insufficient to maintain the pregnancy, due to an abnormality that inhibits the embryo from producing sufficient hCG or to the mother’s ovaries’ failure to respond to the hCG. The levels of estrogen and progesterone during an abnormal pregnancy that result in a first-trimester miscarriage are insufficient to stimulate breast development. As the breasts were never stimulated to grow, the mother normally has no change in breast cancer risk.((Janet R. Daling, Kathleen E. Malone, Lynda F. Voigt, Emily White, and Noel S. Weiss, “Risk of Breast Cancer among Young Women: Relationship to Induced Abortions,​” //Journal of the National Cancer Institute// 86(1994): 1584-1592
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 +This entry draws heavily from [[http://​marri.us/​research/​research-papers/​induced-abortion-and-breast-cancer/​|Induced Abortion and Breast Cancer]].))
  
 =====2. Second-Trimester Miscarriage===== =====2. Second-Trimester Miscarriage=====
  
-Second-trimester spontaneous abortions usually occur due to physical problems (e.g., the umbilical cord twisted around the fetus’s neck). In such cases, estrogen and progesterone levels are normal; mothers’ breasts have therefore undergone the changes that increase breast cancer risk. Because the pregnancy will not continue to term, the natural maturation process that protects the breasts will not be completed, and a mother may have an increased risk of breast cancer.+Second-trimester spontaneous abortions ​(ie. miscarriages) ​usually occur due to physical problems (e.g., the umbilical cord twisted around the fetus’s neck). In such cases, estrogen and progesterone levels are normal; mothers’ breasts have therefore undergone the [[biology_of_the_abortion-breast_cancer_link|changes that increase breast cancer risk]]. Because the pregnancy will not continue to term, the natural maturation process that protects the breasts will not be completed, and a mother may have an increased risk of breast cancer.
  
 =====3. Premature Delivery===== =====3. Premature Delivery=====
  
-If a mother’s pregnancy does not continue past 32 weeks due to premature delivery, she will not get the protective effect of pregnancy against breast cancer, because her breast tissue will not have developed enough Type 4 cancer-resistant lobules.+If a mother’s pregnancy does not continue past 32 weeks due to premature delivery, she will not get the [[effects_of_pregnancy_on_breast_cancer_risks|protective effect of pregnancy]] against breast cancer, because her breast tissue will not have developed enough Type 4 cancer-resistant lobules.
  
 =====4. Induced Abortion===== =====4. Induced Abortion=====
  
-If a woman has an induced abortion (presumably prior to 32 weeks), she has the same vulnerability as a woman delivering prematurely or experiencing spontaneous abortion not caused by low hormone levels, because her breasts will contain an increased number of Type 1 and Type 2 lobules and will not have developed sufficient cancer-resistant Type 4 lobules. The longer a woman is pregnant before an induced abortion, the more cancer-vulnerable Type 1 and Type 2 lobules she will develop.+If a woman has an [[abortion-breast_cancer_link|induced abortion]] (presumably prior to 32 weeks), she has the same vulnerability as a woman delivering prematurely or experiencing spontaneous abortion not caused by low hormone levels, because her breasts will contain an increased number of Type 1 and Type 2 lobules and will not have developed sufficient cancer-resistant Type 4 lobules. The longer a woman is pregnant before an induced abortion, the more cancer-vulnerable Type 1 and Type 2 lobules she will develop.
  
 Repeated induced abortions also increase a woman’s risk of premature birth. ​ Very premature delivery may affect a woman’s future breast health. Repeated induced abortions also increase a woman’s risk of premature birth. ​ Very premature delivery may affect a woman’s future breast health.